Purpose. An unusual case of nasal-type natural killer/T-cell lymphoma (NKTL) of the orbit is reported.
Methods. The clinical history, computed tomography, magnetic resonance imaging, and biopsy specimen
of a 29-year-old man with a right orbital lymphoma were evaluated.
Results. The patient initially presented with conjunctival injection and had flu-like symptoms before
developing right proptosis and reduced vision; imaging showed a diffuse infiltrative process throughout
the orbit. Orbital biopsy revealed angiodestruction with prominent necrosis, and angiocentric
lymphoma growth and lymphoma cells were positively stained for CD3, CD20, CD45RO, CD56, cytotoxic
molecules (granzyme B and T-cell intracellular antigen-1), and Epstein-Barr virus.
Conclusions. NKTL is rare and may present acutely; the imaging findings presented serve to highlight
the radiologic features of the disease.