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Mean platelet volume in pseudoexfoliation syndrome and glaucoma

Mean platelet volume in pseudoexfoliation syndrome and glaucoma

Eur J Ophthalmol 2014; 24(1): 71 - 75

Article Type: ORIGINAL ARTICLE

Article Subject: Glaucoma

DOI:10.5301/ejo.5000340

Authors

Fatih Mehmet Türkcü, Harun Yüksel, Alparslan Sahin, Yasin Cinar, Hatice Yüksel, Kürsat Cingü, Muhammed Sahin, Adnan Yildirim, Ihsan Çaça

Corresponding author

  • Fatih Mehmet Türkcü
  • Dicle Üniversitesi Tıp Fakültesi
  • Sur/Diyarbakır Turkey
  • turkcufm@gmail.com

Abstract

Purpose: Pseudoexfoliation (PEX) syndrome (PES) is characterized by the widespread deposition of abnormal extracellular fibrillary material on many ocular and extraocular tissues. The objective of this study was to evaluate the association among PES, PEX glaucoma (PEG), and mean platelet volume (MPV).

Methods: Forty patients with PES (mean age 62.6 ± 7.8 years), 31 with PEG (mean age 65.9 ± 6.6 years), and 37 healthy individuals (control group) (mean age 64.0 ± 7.1 years) were included in the study. The MPV of the 3 groups were compared.

Results: Age and sex distribution were similar among groups (p>0.05). Mean MPV in PES, PEG, and control groups were 9.59 ± 0.94 fl, 9.53 ± 0.80 fl, and 7.7 ± 0.67 fl, respectively. In the PEX group, MPV values ​​were significantly higher than in the control group (p<0.05). However, there was no difference between the PES and PEG groups (p>0.05).

Conclusions: The MPV values in both groups with PEX were higher than those in the healthy group.

Article History

Disclosures

Financial Support: No financial support was received for this submission.
Conflict of Interest Statement: None of the authors has conflict of interest with this submission.

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Authors

Affiliations

  • Department of Ophthalmology, Dicle University Faculty of Medicine, Diyarbakir - Turkey
  • Department of Biochemistry, Dicle University Faculty of Medicine, Diyarbakir - Turkey

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