Effect of pharmacologic pupil dilation on OLCR optical biometry measurements for IOL predictions
Purpose: To determine the possible influence of pupil dilation on intraocular lens (IOL) power predictions made using optical biometry with Lenstar LS 900® (Haag-Streit AG, Koeniz, Switzerland).
Methods: A total of 72 eyes of 72 patients scheduled to undergo cataract surgery were prospectively examined using the optical low-coherence reflectometry (OLCR) optical biometer before and after pupil dilation with tropicamide 1%. The measurements made were axial length, central corneal thickness, anterior chamber depth (ACD), lens thickness, mean keratometry, corneal diameter (CD), and pupil diameter. Holladay II and SRK/T formulas were used to calculate IOL power. Agreement between the 2 measurement modes (with and without dilation) was assessed by calculating intraclass correlation coefficients (ICC) and constructing Bland-Altman plots.
Results: The mean age of the patients was 74.71 ± 7.53 years (range 56-90). Among the variables determined, only ACD varied significantly according to pupil dilation (p<0.001). The ICC data revealed excellent intraobserver correlation between measurements made with and without dilation, except for CD. The IOL power predictions were unmodified.
Conclusions: The use of pupil dilation does not seem to influence measurements and IOL predictions made using this OLCR optical biometer.
Eur J Ophthalmol 2014; 24(1): 53 - 57
Article Type: ORIGINAL RESEARCH ARTICLE
Article Subject: Lens/Cataract
Pedro Arriola-Villalobos, David DÍaz-Valle, Nuria Garzo´n, Jorge Ruiz-Medrano, Cristina Fernández-Pe´rez, Nicolás Alejandre-Alba, Julián GarcÍa-Feijoo´
• Accepted on 27/05/2013
• Available online on 17/06/2013
• Published in print on 20/11/2013
Financial Support: No financial support was received for this submission.
Conflict of Interest Statement: None of the authors has conflict of interest with this submission.
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Ophthalmology, Hospital Clínico San Carlos, Instituto de Investigaci.n Sanitaria del Hospital Cl.nico San Carlos (IdISSC), Madrid - Spain
Departamento de Oftalmología y ORL, Facultad de Medicina, Ophthalmology, Hospital Clínico San Carlos, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid - Spain
Instituto de Oftalmología Avanzada, Madrid - Spain
Research Support Unit, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid - Spain
Ophthalmology, Fundación Jiménez Díaz, Madrid - Spain
Instituto de Salud Carlos III (Proyecto RD 07/0062: Patología ocular del envejecimiento, calidad visual y calidad de vida), Madrid - Spain
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