To evaluate the optic nerve head parameters and peripapillary retinal nerve fiber layer using spectral-domain optical coherence tomography (SD-OCT) in a systemic sclerosis (SSc) cohort and age-matched controls to determine whether SSc patients have an increased risk of normal-tension glaucoma (NTG).
We examined 30 patients (3 male, 27 female) with SSc and 28 age- and sex-matched controls. Retinal nerve fiber and optic disc morphology were evaluated using Cirrus SD-OCT.
Optic disc morphology measurements including disc area, rim area, average and vertical cup/disc (C/D) ratio, and cup volume were not significantly different between the study groups. The average and 4-quadrant retinal nerve fiber layer (RNFL) measurements of the C/D >0.3 subgroups were not significantly different in the patients and controls. These values were also similar for the C/D >0.5 subgroups except that the average inferior quadrant RNFL thickness of the right eyes in the patient subgroup was significantly thinner than in the control subgroup (p<0.05).
Our SSc cohort had relatively shorter disease duration but increased prevalence of early glaucomatous damage signs. Our findings indicate that SSc is a risk factor for developing normal-tension glaucoma. Further studies combined with visual field evaluation are necessary to identify the long-term glaucomatous effects of SSc.
Eur J Ophthalmol 2017; 27(3): 281 - 284
Article Type: ORIGINAL RESEARCH ARTICLE
AuthorsSevinc Sahin-Atik, Feray Koc, Sirin Akin-Sari, Mustafa Ozmen
- • Accepted on 14/06/2016
- • Available online on 16/07/2016
- • Published in print on 11/05/2017
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- Sahin-Atik, Sevinc [PubMed] [Google Scholar] 1, * Corresponding Author (firstname.lastname@example.org)
- Koc, Feray [PubMed] [Google Scholar] 1
- Akin-Sari, Sirin [PubMed] [Google Scholar] 2
- Ozmen, Mustafa [PubMed] [Google Scholar] 3
Department of Ophthalmology, Ataturk Teaching and Research Hospital, Yesilyurt, Izmir - Turkey
Department of Internal Medicine, Bigadic Public Hospital, Balikesir - Turkey
Department of Internal Medicine, Division of Rheumatology, Ataturk Teaching and Research Hospital, Yesilyurt, Izmir - Turkey