To evaluate factors associated with response to intravitreal bevacizumab (IVB) and intravitreal triamcinolone acetonide (IVTA) in diabetic macular edema (DME).
Ninety-one eyes of 88 patients diagnosed with DME were enrolled in this retrospective chart review. Group 1 included eyes that showed good response to IVB. Group 2 included eyes that did not respond to IVB but responded to IVTA. Group 3 included eyes that responded to neither. Clinical factors, HbA1c, and optical coherence tomography (OCT) findings including patterns of macular edema were compared among the 3 groups.
A total of 44, 27, and 20 eyes were included in groups 1, 2, and 3, respectively. HbA1c was higher in group 3 than in the other groups. Proportion of full (combination of all patterns) type edema was higher in group 3 than in the other 2 groups. In group 1, the proportion of sponge-like diffuse retinal thickening type was higher and cystoid macular edema type was lower than in the other groups.
The degree of diabetic control and morphologic subtypes with OCT should be considered to better predict the prognosis after treatment in DME.
Eur J Ophthalmol 2017; 27(6): 746 - 750
Article Type: ORIGINAL RESEARCH ARTICLE
AuthorsTai K. Kim, Hye Y. Shin, Su Y. Kim, Young C. Lee, Mee Y. Lee
- • Accepted on 26/03/2017
- • Available online on 11/04/2017
- • Published in print on 08/11/2017
This article is available as full text PDF.
- Kim, Tai K. [PubMed] [Google Scholar]
- Shin, Hye Y. [PubMed] [Google Scholar]
- Kim, Su Y. [PubMed] [Google Scholar]
- Lee, Young C. [PubMed] [Google Scholar]
- Lee, Mee Y. [PubMed] [Google Scholar] , * Corresponding Author (email@example.com)
Department of Ophthalmology and Visual Science, Uijeongbu St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Uijeongbu-si, Gyeonggi-do - Korea