To evaluate the thickness of the peripapillary retinal nerve fiber layer (RNFL), total macula, macular ganglion cell layer (GCL), inner plexiform layer (IPL), and choroid in pediatric migraine patients and compare the values with healthy subjects.
This observational and cross-sectional study included 40 patients in the migraine group and 40 healthy control subjects. The thickness of the peripapillary RNFL, total macula, GCL, and IPL was analyzed with spectral-domain optic coherence tomography, while choroidal thickness was analyzed with the enhanced depth imaging protocol. All measurements of the migraine patients were taken in the attack-free period. Right eye selected per subject was included in the study.
There was no significant difference between the 2 groups in age or sex (p>0.05). The peripapillary RNFL thickness was not significantly different between the 2 groups in any quadrant. The total macula, GCL, and IPL thickness were also not significantly different in the 9 separate macular areas defined on the basis of the Early Treatment Diabetic Retinopathy Study (p>0.05). The choroidal thickness at 5 different measurement points was not statistically significantly different between migraine patients during the attack-free period and the healthy subjects (p>0.05).
Childhood migraine does not cause changes in posterior ocular structure parameters.
Eur J Ophthalmol 2017; 27(4): 495 - 501
Article Type: ORIGINAL RESEARCH ARTICLE
AuthorsPinar Nalcacioglu, Ayse G. Taslipinar Uzel, Mehmet M. Uzel, Nurullah Cagil, Aysegul N. Citak Kurt
- • Accepted on 19/09/2016
- • Available online on 10/11/2016
- • Published in print on 26/06/2017
This article is available as full text PDF.
- Nalcacioglu, Pinar [PubMed] [Google Scholar] 1, * Corresponding Author (email@example.com)
- Taslipinar Uzel, Ayse G. [PubMed] [Google Scholar] 2
- Uzel, Mehmet M. [PubMed] [Google Scholar] 3
- Cagil, Nurullah [PubMed] [Google Scholar] 1
- Citak Kurt, Aysegul N. [PubMed] [Google Scholar] 4
Department of Ophthalmology, Faculty of Medicine, Yildirim Beyazit University, Ankara - Turkey
Ataturk Training and Research Hospital, Ankara - Turkey
Ulucanlar Eye Training and Research Hospital, Ankara - Turkey
Department of Pediatric Neurology, Faculty of Medicine, Yildirim Beyazit University, Ankara - Turkey