Anti-vascular endothelial growth factor for unilateral acute idiopathic maculopathy



To describe a case of unilateral acute idiopathic maculopathy (UAIM) response to intravitreal therapy with aflibercept (Eylea).


Retrospective case report.


A 36-year-old woman with sudden visual impairment and central scotoma was found to have a UAIM in her left eye. Three weeks after continuous worsening of her visual acuity and central scotoma, the patient was treated with intravitreal injections of aflibercept. The visual acuity increased and the macula lesion regressed, causing macula scarring after 2 injections.


Intravitreal injections of aflibercept could be a therapy option in patients with UAIM without signs of spontaneous resolution of the clinical manifestations and visual improvement.

Post author correction

Article Type: CASE REPORT

Article Subject: Retina MED



Georgios Mylonas, Franz Prager, Barbara Wetzel, Panagiotis Malamos, Gabor Deak, Michael Amon

Article History


Financial support: No financial support was received for this submission.
Conflict of interest: None of the authors has conflict of interest with this submission.

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  • Department of Ophthalmology, Academic Teaching Hospital of St. John of God, Vienna - Austria
  • Sigmund Freud University, Medical School, Vienna - Austria
  • 1st Department of Ophthalmology, “G. Gennimatas” General Hospital of Athens, University of Athens, Psychiko, Athens - Greece
  • Department of Ophthalmology, Medical University of Vienna, Vienna - Austria

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