To assess the impact of metabolic syndrome (MetS) on the peripapillary choroidal thickness (PPCT) and to characterize the PPCT in a Portuguese population.
This prospective study included 104 eyes. Detailed medical and ophthalmic examinations were performed; the PPCT was measured by spectral-domain optical coherence tomography (SD-OCT) using enhanced depth imaging (EDI) modality. The PPCT changes with MetS, as well as with other clinical and demographic factors, were investigated.
The mean PPCT was 142.4 ± 54.0 µm (58-303 µm); it was thickest superiorly, followed by the temporal, nasal, and inferior sectors. The PPCT was significantly associated with axial length (p<0.001), age (p = 0.001), intraocular pressure (IOP) (p = 0.041), weight (p = 0.015), and arterial hypertension (p = 0.044). The presence of MetS was associated with thinner PPCT in all sectors, being statistically significant in the temporal (p = 0.032) and inferotemporal (p = 0.034) sectors.
The choroidal thickness was significantly less in temporal and inferotemporal sectors in patients with MetS than in controls. This may suggest vascular insufficiency around the optic nerve head.
Eur J Ophthalmol 2017; 27(4): 428 - 432
Article Type: ORIGINAL RESEARCH ARTICLE
AuthorsMónica Loureiro, Ana Cristina Braga, Dália Meira, Paula Sepúlveda, Luís Agrelos, Paulo Torres
- • Accepted on 03/11/2016
- • Available online on 21/11/2016
- • Published in print on 26/06/2017
This article is available as full text PDF.
- Loureiro, Mónica [PubMed] [Google Scholar] 1, 2, * Corresponding Author (email@example.com)
- Braga, Ana Cristina [PubMed] [Google Scholar] 3
- Meira, Dália [PubMed] [Google Scholar] 1
- Sepúlveda, Paula [PubMed] [Google Scholar] 1
- Agrelos, Luís [PubMed] [Google Scholar] 1
- Torres, Paulo [PubMed] [Google Scholar] 2, 4
Department of Ophthalmology, Centro Hospitalar de V. N. Gaia/Espinho, Vila Nova de Gaia - Portugal
Institute of Biomedical Sciences Abel Salazar, University of Porto, Porto - Portugal
ALGORITMI Centre, University of Minho, Braga - Portugal
Department of Ophthalmology, Centro Hospitalar do Porto, Porto - Portugal