Amniotic membrane transplantation with narrow-strip conjunctival autograft vs conjunctival autograft for recurrent pterygia
Eur J Ophthalmol 2017; 27(2): 135 - 140
Article Type: ORIGINAL RESEARCH ARTICLE
AuthorsJosé B. Barbosa, Charles Costa De Farias, Flávio E. Hirai, José Á. Pereira Gomes
To compare amniotic membrane transplantation (AMT) associated with narrow-strip conjunctival autograft vs conjunctival autograft alone for the treatment of recurrent pterygium.
In this prospective consecutive interventional study, patients with recurrent pterygium were randomly divided into one of 2 groups; group 1: patients undergoing AMT associated with autologous conjunctival graft; and group 2: patients undergoing conjunctival autograft alone.
Of the 80 operated eyes included in this study, 39 (group 1, mean patient age 52.1 ± 11.7 SD years) underwent AMT associated with narrow-strip conjunctival autograft and 41 (group 2, mean patient age 45.8 ± 12.9 SD years) underwent conjunctival autograft alone. In group 1, 6 eyes (15.4%) had grade 1 pterygium, 19 eyes (48.7%) had grade 2 pterygium, and 14 eyes (35.9%) had grade 3 pterygium. In the second group, 5 eyes (12.2%) had grade 1 pterygium, 18 eyes (43.9%) had grade 2 pterygium, and 14 eyes (35.9%) had grade 3 pterygium. No statistically significant difference was found between the 2 groups (p = 0.752). Of the 39 eyes in group 1, recurrent pterygium was observed in 7 cases (17.9%). However, of the 41 eyes in group 2, recurrent pterygium was observed in only 4 cases (9.75%). No statistically significant difference was found between the 2 groups (p = 0.2684).
The results of this study indicate that conjunctival autograft alone might be a better surgical choice for the treatment of recurrent pterygia than combining it with AMT; however, this second option provides a good surgical alternative in cases where little conjunctival donor tissue is available.
- • Accepted on 21/06/2016
- • Available online on 12/07/2016
- • Published in print on 10/03/2017
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- Barbosa, José B. [PubMed] [Google Scholar] , * Corresponding Author (firstname.lastname@example.org)
- De Farias, Charles Costa [PubMed] [Google Scholar]
- Hirai, Flávio E. [PubMed] [Google Scholar]
- Pereira Gomes, José Á. [PubMed] [Google Scholar]
Department of Ophthalmology, Federal University of São Paulo (UNIFESP), São Paulo - Brazil