Comparison of short-term refractive surgery outcomes after wavefront-guided versus non-wavefront-guided LASIK



To evaluate and compare visual and refractive outcomes after laser-assisted in situ keratomileusis (LASIK) surgery for the correction of myopia or myopic astigmatism using 3 different treatment protocols.


We included 736 eyes of 369 patients (age 18-62 years) divided into 3 groups: 235 eyes of 118 patients (MEL80 group) undergoing LASIK using optimized aspheric ablation profiles (MEL80 excimer laser; Carl Zeiss Meditec), 248 eyes of 124 patients (Wavescan group) undergoing wavefront-guided (WFG) LASIK (STAR S4IR excimer laser + Wavescan aberrometer; Abbott Medical Optics), and 253 eyes of 127 patients (iDesign group) undergoing WFG LASIK (STAR S4IR excimer laser + iDesign system; Abbott Medical Optics). Visual and refractive outcomes were evaluated 2 months after surgery.


A total of 91% (215/235), 95% (237/248), and 99% (251/253) of eyes achieved a postoperative uncorrected distance visual acuity of 0.0 logMAR (≈20/20) in the MEL80, Wavescan, and iDesign groups, respectively. Postoperative spherical equivalent (SE) was within ±0.5 D in 95% (223/235), 98% (242/248), and 100% (253/253) of eyes in these same 3 groups, respectively. Likewise, manifest cylinder was below 0.50 D in 95% (223/235), 97% (241/248), and 100% (253/253) of eyes. Significant differences in postoperative SE and cylinder were found between the MEL80 and iDesign groups (p<0.05).


All evaluated LASIK treatment protocols are predictable and effective for the correction of myopia. The treatment planned with a high resolution aberrometer obtained the best postoperative refractive outcomes.

Eur J Ophthalmol 2016; 26(6): 529 - 535




Sarah Moussa, Alois Dexl, Eva Maria Krall, Marie Dietrich, Eva-Maria Arlt, Günther Grabner, Josef Ruckhofer

Article History


Financial support: This research was funded with an unrestricted educational grant from Abbott Medical Optics Inc.
Conflict of interest: None of the authors has conflict of interest with this submission.
Meeting presentation: London, September 13-17 2014, XXXII ESCRS Congress 2014.

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  • Department of Ophthalmology and Optometry, Paracelsus Medical University of Salzburg, Salzburg - Austria

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