To evaluate the outcome of combined Ahmed glaucoma valve (AGV) and phacoemulsification with posterior chamber intraocular lens implantation under infliximab in refractory uveitic glaucoma (UG).
In this prospective interventional case series, 26 eyes of 26 patients with refractory UG underwent surgery under intravenous infliximab. The success rate was defined as intraocular pressure (IOP) 5 to 21 mm Hg with or without antiglaucoma medications (AGM), without additional glaucoma surgical intervention.
The mean IOP (37.8 ± 11.86 to 12.2 ± 2.8 mm Hg; p<0.0001) and mean number of AGM (3.4 ± 1.2 to 0.4 ± 0.1; p<0.001) were significantly reduced after surgery at 2 years. Kaplan-Meier survival analysis showed a cumulative probability of success for IOP control of 92% at 2 years of follow-up.
Combined AGV and phacoemulsification is an effective treatment for controlling refractory UG with complicated cataract under infliximab.
Post author correction
Article Type: ORIGINAL RESEARCH ARTICLE
Article Subject: Glaucoma
AuthorsJitendra K.S. Parihar, Jaya Kaushik, Vaibhav K. Jain, Hemant S. Trehan, Avinash Mishra, Vinod K. Baranwal
- • Accepted on 22/08/2017
- • Available online on 11/09/2017
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- Parihar, Jitendra K.S. [PubMed] [Google Scholar] 1, * Corresponding Author (firstname.lastname@example.org)
- Kaushik, Jaya [PubMed] [Google Scholar] 2
- Jain, Vaibhav K. [PubMed] [Google Scholar] 3
- Trehan, Hemant S. [PubMed] [Google Scholar] 4
- Mishra, Avinash [PubMed] [Google Scholar] 5
- Baranwal, Vinod K. [PubMed] [Google Scholar] 6
Department of Ophthalmology, Army Hospital Research and Referral, New Delhi - India
Department of Ophthalmology, Command Hospital (Western Command) and PG Medical Institute, Chandimandir Panchkula, Haryana - India
Department of Ophthalmology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow - India
Department of Ophthalmology, INHS Asvini and PG Medical Institute, Kolaba, Mumbai, Maharashtra - India
Department of Ophthalmology, Command Hospital (Eastern Command) and PG Medical Institute, Kolkata, West Bengal - India
Department of Ophthalmology, Base Hospital Delhi Cantt and Army College of Medical Sciences, New Delhi - India