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Combined Ahmed valve and phacoemulsification with intraocular lens implantation under infliximab in refractory uveitic glaucoma

Abstract

Purpose

To evaluate the outcome of combined Ahmed glaucoma valve (AGV) and phacoemulsification with posterior chamber intraocular lens implantation under infliximab in refractory uveitic glaucoma (UG).

Methods

In this prospective interventional case series, 26 eyes of 26 patients with refractory UG underwent surgery under intravenous infliximab. The success rate was defined as intraocular pressure (IOP) 5 to 21 mm Hg with or without antiglaucoma medications (AGM), without additional glaucoma surgical intervention.

Results

The mean IOP (37.8 ± 11.86 to 12.2 ± 2.8 mm Hg; p<0.0001) and mean number of AGM (3.4 ± 1.2 to 0.4 ± 0.1; p<0.001) were significantly reduced after surgery at 2 years. Kaplan-Meier survival analysis showed a cumulative probability of success for IOP control of 92% at 2 years of follow-up.

Conclusions

Combined AGV and phacoemulsification is an effective treatment for controlling refractory UG with complicated cataract under infliximab.

Post author correction

Article Type: ORIGINAL RESEARCH ARTICLE

Article Subject: Glaucoma

DOI:10.5301/ejo.5001032

Authors

Jitendra K.S. Parihar, Jaya Kaushik, Vaibhav K. Jain, Hemant S. Trehan, Avinash Mishra, Vinod K. Baranwal

Article History

Disclosures

Financial support: No financial support was received for this submission.
Conflict of interest: None of the authors has conflict of interest with this submission.

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Authors

Affiliations

  •  Department of Ophthalmology, Army Hospital Research and Referral, New Delhi - India
  •  Department of Ophthalmology, Command Hospital (Western Command) and PG Medical Institute, Chandimandir Panchkula, Haryana - India
  •  Department of Ophthalmology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow - India
  •  Department of Ophthalmology, INHS Asvini and PG Medical Institute, Kolaba, Mumbai, Maharashtra - India
  •  Department of Ophthalmology, Command Hospital (Eastern Command) and PG Medical Institute, Kolkata, West Bengal - India
  •  Department of Ophthalmology, Base Hospital Delhi Cantt and Army College of Medical Sciences, New Delhi - India

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